Decoding the DNA blueprints for building a brain, now in 3D!
Using novel techniques to map 3D chromatin interactions in vivo, Giacomo Cavalli’s team generated contact maps from purified mouse brain […]
Daily Archives: October 24, 2017
Multi-scale 3D genome rewiring during mouse neural development
Bonev, B., Mendelson Cohen, N., Szabo, Q., Fritsch, L., Papadopoulos, G., Lubling, Y., Xu, X., Lv, X., Hugnot, J.-P., Tanay, A, and Cavalli, G.
Cell Volume 171, Issue 3, p557–572.e24, 19 October 2017
DOI: http://dx.doi.org/10.1016/j.cell.2017.09.043
Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions
Cattoni DI, Cardozo Gizzi AM, Georgieva M, DiStefano M, Valeri A, Chamousset D, Houbron Ch, Déjardin S, Fiche JB, González I, Chang JM, Sexton T, Marti-Renom MA, Bantignies F, Cavalli G and Nollmann M
Nature Communications 8, 1753
https://www.biorxiv.org/content/early/2017/10/24/159814