Work Package 1 • Project management
- Milestone 1 – First annual report submitted 1/11/2016
- Milestone 2 – Second annual report submitted 1/11/2017
- Milestone 3 – Third annual and final reports submitted 1/11/2018
Work Package 2 • Outreach, Training and Exploitation Plan
- Milestone 4 – Publication of project factsheet 14/01/2016
- Milestone 5 – Setting the project website 15/01/2016
- Milestone 6 – Initial exploitation plan 1/05/2017
- Milestone 7 – Final exploitation plan 1/11/2018
- Milestone 8 – First training workshop 1/05/2017
- Milestone 9 – Second training workshop 1/11/2018
Work Package 3 • Multi-scale visualization of the nucleus
- Milestone 10 – JavaScript-based browser for 1D genomic data taking inputs 3D models and genome annotations 9/06/2016
- Milestone 11 – A working version of the 3D genome browser connecting 1D and 2D panels 1/11/2016
- Milestone 12 – A working version of the 3D genome browser connecting 1D, 2D and 3D panels 1/11/2017
Work Package 4 • Data management
- Milestone 13 – Establishment of open source software development infrastructure 29/06/2016
- Milestone 14 – Publication of public data APIs 1/05/2017
- Milestone 15 – Deployment of components to public and private clouds 1/11/2017
- Milestone 16 – Online documentation and training materials available 1/11/2017
Work Package 5 • Computational Infrastructure and Deployment
- Milestone 17 – Early prototypes of the computational infrastructure 5/09/2016
- Milestone 18 – User support tools available 1/11/2016
- Milestone 19 – Programming models release 1/09/2017
- Milestone 20 – Computational infrastructure final version 1/09/2018
Work Package 6 • Analysis Tools
- Milestone 21 – Production of the first 3D/4D models of protein-DNA complexes 20/05/2016
- Milestone 22 – 4D data from the ABC project processed to generate database of DNA sequence-flexibility relationship 20/05/2016
- Milestone 23 – Tools to predict DNA sequence-flexibility relationship 1/11/2016
- Milestone 24 – Comparison of software to calculate and analyse FISH data 1/11/2016
- Milestone 25 – Comparison of software to calculate and analyse 3C data 1/11/2016
- Milestone 26 – Comparison of different methodologies to add protein-induced perturbations into predictions of DNA sequence-flexibility relationship 1/11/2017
Work Package 7 • Pilot projects
- Milestone 27 – Production of 3D genome maps of normal cells as well as senescent cells 1/05/2017
- Milestone 28 – Obtention of yeast Hi-C and FISH data 1/05/2017
- Milestone 29 – ABC data entered into the MuG 3D/4D databases 1/12/2016
- Milestone 30 – ABC data analysed and DNA sequence-dependent flexibility data obtained 1/04/2017
- Milestone 31 – MuG databases and visualisers to identify TFs with binding coupled to DNA topological constraints 1/08/2017
- Milestone 32 – Simulations of selected DNA-TFs complexes 1/02/2018
- Milestone 33 – Analysis of TFs 3D/4D data and correlation with ABC predictions 1/06/2018